In these cases the patient s immune system is dismantled through chemotherapy before the immune system is re started with their own hscs similar to how these same cells are used to treat cancers like leukemias.
Ms and cord blood stem cells.
Hematopoietic stem cells hematopoietic stem cells hsc are found in bone marrow blood and umbilical cord.
How stem cells treat multiple sclerosis.
Hscs haematopoietic stem cells adult stem cells that are found in bone marrow and blood.
Some doctors use a type of stem cell treatment called hematopoietic stem cell transplantation hsct to treat rrms.
Mscs mesenchymal stem cells adult stem cells found in several places in the body including the bone marrow skin and fat tissue.
The transplanted stem cells replace the individual s malfunctioning immune system.
Compared to bone marrow cells cord blood is safer quicker and easier to match.
Stem cells can be easily isolated from different sources of the body including peripheral blood adipose and bone marrow tissues umbilical cord blood and placenta.
There are a few schools of thought on how cord blood and cord tissue can treat multiple sclerosis.
The infused stem cells replace damaged tissue within the central nervous system.
The other strategy being applied is to utilize hematopoietic stem cells hscs which are commonly derived from cord blood.
They produce cells which help other stem cells function properly.
To that end multiple groups have now transplanted glial progenitor cells to treat animal models of ms.
There is a clinical trial underway for ms treatment using stem cells.
Hscs are capable of producing all of the cells that make up the blood and the immune system.
Human and pluripotent stem cell derived glial progenitor cells have significantly increased and often rescued the lifespans of mice with demyelination with effective remyelination and recovery of lost neurological functions.
But more research is needed to know.
Cord blood may be the most potent source of cells in the body even compared to bone marrow.
Treatment with umbilical cord stem cells was found to be safe and leads to sustained improvements in disability and brain lesions of multiple sclerosis ms patients according to a clinical trial.
Below are some applications for stem cells that are currently being tested for ms.
Cord blood stem cells are in clinical trials for ms treatment.
These stem cells are capable of maturing into all cells that comprise the blood and immune system.